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Found 18 results
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2017
Dimopoulos MA
,
A Stewart K
,
Masszi T
,
Spicka I
,
Oriol A
,
Hajek R
,
Rosiñol L
,
Siegel D
,
Mihaylov GG
,
Goranova-Marinova V
et al.
. 2017.
Carfilzomib, lenalidomide, and dexamethasone in patients with relapsed multiple myeloma categorised by age: secondary analysis from the phase 3 ASPIRE study.
.
Br J Haematol. 177(3):404-413.
Dimopoulos MA
,
Goldschmidt H
,
Niesvizky R
,
Joshua D
,
Chng W-J
,
Oriol A
,
Orlowski RZ
,
Ludwig H
,
Facon T
,
Hajek R
et al.
. 2017.
Carfilzomib or bortezomib in relapsed or refractory multiple myeloma (ENDEAVOR): an interim overall survival analysis of an open-label, randomised, phase 3 trial.
.
Lancet Oncol. 18(10):1327-1337.
Dimopoulos MA
,
Stewart AK
,
Masszi T
,
Špička I
,
Oriol A
,
Hájek R
,
Rosiñol L
,
Siegel D
,
Mihaylov GG
,
Goranova-Marinova V
et al.
. 2017.
Carfilzomib-lenalidomide-dexamethasone vs lenalidomide-dexamethasone in relapsed multiple myeloma by previous treatment.
.
Blood Cancer J. 7(4):e554.
Castillo JJ
,
Jurczyszyn A
,
Brozova L
,
Crusoe E
,
Czepiel J
,
Davila J
,
Dispenzieri A
,
Eveillard M
,
Fiala MA
,
Ghobrial IM
et al.
. 2017.
IgM myeloma: A multicenter retrospective study of 134 patients.
.
Am J Hematol. 92(8):746-751.
Moreau P
,
Joshua D
,
Chng W-J
,
Palumbo A
,
Goldschmidt H
,
Hájek R
,
Facon T
,
Ludwig H
,
Pour L
,
Niesvizky R
et al.
. 2017.
Impact of prior treatment on patients with relapsed multiple myeloma treated with carfilzomib and dexamethasone vs bortezomib and dexamethasone in the phase 3 ENDEAVOR study.
.
Leukemia. 31(1):115-122.
Ou Y
,
Doshi S
,
Nguyen A
,
Jonsson F
,
Aggarwal S
,
Rajangam K
,
Dimopoulos MA
,
A Stewart K
,
Badros A
,
Papadopoulos KP
et al.
. 2017.
Population Pharmacokinetics and Exposure-Response Relationship of Carfilzomib in Patients With Multiple Myeloma.
.
J Clin Pharmacol. 57(5):663-677.
2016
Jurczyszyn A
,
Nahi H
,
Avivi I
,
Gozzetti A
,
Niesvizky R
,
Yadlapati S
,
Jayabalan DS
,
Robak P
,
Pika T
,
Andersen KT
et al.
. 2016.
Characteristics and outcomes of patients with multiple myeloma aged 21-40 years versus 41-60 years: a multi-institutional case-control study.
.
Br J Haematol. 175(5):884-891.
2015
Niesvizky R
,
Flinn IW
,
Rifkin R
,
Gabrail N
,
Charu V
,
Clowney B
,
Essell J
,
Gaffar Y
,
Warr T
,
Neuwirth R
et al.
. 2015.
Community-Based Phase IIIB Trial of Three UPFRONT Bortezomib-Based Myeloma Regimens.
.
J Clin Oncol. 33(33):3921-9.
Niesvizky R
,
Badros AZ
,
Costa LJ
,
Ely SA
,
Singhal SB
,
Stadtmauer EA
,
Haideri NA
,
Yacoub A
,
Hess G
,
Lentzsch S
et al.
. 2015.
Phase 1/2 study of cyclin-dependent kinase (CDK)4/6 inhibitor palbociclib (PD-0332991) with bortezomib and dexamethasone in relapsed/refractory multiple myeloma.
.
Leuk Lymphoma. 56(12):3320-8.
Vij R
,
Wang M
,
Jagannath S
,
Niesvizky R
,
Jakubowiak AJ
,
Kavalerchik E
,
Huang M
,
Siegel DS
. 2015.
Serum free light chain reduction correlates with response and progression-free survival following carfilzomib therapy in relapsed/refractory multiple myeloma.
.
Leuk Lymphoma. 56(10):2959-61.
2014
Kumar SK
,
Bensinger WI
,
Zimmerman TM
,
Reeder CB
,
Berenson JR
,
Berg D
,
Hui A-M
,
Gupta N
,
Di Bacco A
,
Yu J
et al.
. 2014.
Phase 1 study of weekly dosing with the investigational oral proteasome inhibitor ixazomib in relapsed/refractory multiple myeloma.
.
Blood. 124(7):1047-55.
Mark TM
,
Bowman IA
,
Rossi AC
,
Shah M
,
Rodriguez M
,
Quinn R
,
Pearse RN
,
Zafar F
,
Pekle K
,
Jayabalan D
et al.
. 2014.
Thalidomide, clarithromycin, lenalidomide and dexamethasone therapy in newly diagnosed, symptomatic multiple myeloma.
.
Leuk Lymphoma. 55(12):2842-9.
2013
Badros AZ
,
Vij R
,
Martin T
,
Zonder JA
,
Kunkel L
,
Wang Z
,
Lee S
,
Wong AF
,
Niesvizky R
. 2013.
Carfilzomib in multiple myeloma patients with renal impairment: pharmacokinetics and safety.
.
Leukemia. 27(8):1707-14.
Rosenbaum C
,
Jasielec J
,
Laubach J
,
Prada CPaba
,
Richardson P
,
Jakubowiak AJ
. 2013.
Evolving strategies in the initial treatment of multiple myeloma.
.
Semin Oncol. 40(5):592-601.
Siegel D
,
Martin T
,
Nooka A
,
R Harvey D
,
Vij R
,
Niesvizky R
,
Badros AZ
,
Jagannath S
,
McCulloch L
,
Rajangam K
et al.
. 2013.
Integrated safety profile of single-agent carfilzomib: experience from 526 patients enrolled in 4 phase II clinical studies.
.
Haematologica. 98(11):1753-61.
Wang M
,
Martin T
,
Bensinger W
,
Alsina M
,
Siegel DS
,
Kavalerchik E
,
Huang M
,
Orlowski RZ
,
Niesvizky R
. 2013.
Phase 2 dose-expansion study (PX-171-006) of carfilzomib, lenalidomide, and low-dose dexamethasone in relapsed or progressive multiple myeloma.
.
Blood. 122(18):3122-8.
2008
Mark T
,
Stern J
,
Furst JR
,
Jayabalan D
,
Zafar F
,
Larow A
,
Pearse RN
,
Harpel J
,
Shore T
,
Schuster MW
et al.
. 2008.
Stem cell mobilization with cyclophosphamide overcomes the suppressive effect of lenalidomide therapy on stem cell collection in multiple myeloma.
.
Biol Blood Marrow Transplant. 14(7):795-8.
2007
Niesvizky R
,
Naib T
,
Christos PJ
,
Jayabalan D
,
Furst JR
,
Jalbrzikowski J
,
Zafar F
,
Mark T
,
Lent R
,
Pearse RN
et al.
. 2007.
Lenalidomide-induced myelosuppression is associated with renal dysfunction: adverse events evaluation of treatment-naïve patients undergoing front-line lenalidomide and dexamethasone therapy.
.
Br J Haematol. 138(5):640-3.