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M
Mark T
,
Niesvizky R
,
Coleman M
. 2009.
Novel agents in myeloma: an exciting saga.
.
Cancer. 115(2):236-42.
Moreau P
,
Joshua D
,
Chng W-J
,
Palumbo A
,
Goldschmidt H
,
Hájek R
,
Facon T
,
Ludwig H
,
Pour L
,
Niesvizky R
et al.
. 2017.
Impact of prior treatment on patients with relapsed multiple myeloma treated with carfilzomib and dexamethasone vs bortezomib and dexamethasone in the phase 3 ENDEAVOR study.
.
Leukemia. 31(1):115-122.
N
Nayar U
,
Sadek J
,
Reichel J
,
Hernandez-Hopkins D
,
Akar G
,
Barelli PJ
,
Sahai MA
,
Zhou H
,
Totonchy J
,
Jayabalan D
et al.
. 2017.
Identification of a nucleoside analog active against adenosine kinase-expressing plasma cell malignancies.
.
J Clin Invest. 127(6):2066-2080.
Niesvizky R
,
Naib T
,
Christos PJ
,
Jayabalan D
,
Furst JR
,
Jalbrzikowski J
,
Zafar F
,
Mark T
,
Lent R
,
Pearse RN
et al.
. 2007.
Lenalidomide-induced myelosuppression is associated with renal dysfunction: adverse events evaluation of treatment-naïve patients undergoing front-line lenalidomide and dexamethasone therapy.
.
Br J Haematol. 138(5):640-3.
Niesvizky R
. 2013.
Immunomodulatory agents changing the landscape of multiple myeloma treatment.
.
Crit Rev Oncol Hematol. 88 Suppl 1:S1-4.
Niesvizky R
,
Flinn IW
,
Rifkin R
,
Gabrail N
,
Charu V
,
Clowney B
,
Essell J
,
Gaffar Y
,
Warr T
,
Neuwirth R
et al.
. 2015.
Community-Based Phase IIIB Trial of Three UPFRONT Bortezomib-Based Myeloma Regimens.
.
J Clin Oncol. 33(33):3921-9.
Niesvizky R
,
Coleman M
,
Mark T
. 2010.
Best practices in the management of newly diagnosed multiple myeloma patients who will not undergo transplant.
.
Oncology (Williston Park). 24(3 Suppl 2):14-21.
Niesvizky R
,
Jayabalan DS
,
Christos PJ
,
Furst JR
,
Naib T
,
Ely S
,
Jalbrzikowski J
,
Pearse RN
,
Zafar F
,
Pekle K
et al.
. 2008.
BiRD (Biaxin [clarithromycin]/Revlimid [lenalidomide]/dexamethasone) combination therapy results in high complete- and overall-response rates in treatment-naive symptomatic multiple myeloma.
.
Blood. 111(3):1101-9.
Niesvizky R
,
Martínez-Baños D
,
Jalbrzikowski J
,
Christos P
,
Furst J
,
De Sancho M
,
Mark T
,
Pearse R
,
Mazumdar M
,
Zafar F
et al.
. 2007.
Prophylactic low-dose aspirin is effective antithrombotic therapy for combination treatments of thalidomide or lenalidomide in myeloma.
.
Leuk Lymphoma. 48(12):2330-7.
Niesvizky R
,
Ely S
,
Mark T
,
Aggarwal S
,
Gabrilove JL
,
Wright JJ
,
Chen-Kiang S
,
Sparano JA
. 2011.
Phase 2 trial of the histone deacetylase inhibitor romidepsin for the treatment of refractory multiple myeloma.
.
Cancer. 117(2):336-42.
Niesvizky R
,
Badros AZ
,
Costa LJ
,
Ely SA
,
Singhal SB
,
Stadtmauer EA
,
Haideri NA
,
Yacoub A
,
Hess G
,
Lentzsch S
et al.
. 2015.
Phase 1/2 study of cyclin-dependent kinase (CDK)4/6 inhibitor palbociclib (PD-0332991) with bortezomib and dexamethasone in relapsed/refractory multiple myeloma.
.
Leuk Lymphoma. 56(12):3320-8.
O
Ou Y
,
Doshi S
,
Nguyen A
,
Jonsson F
,
Aggarwal S
,
Rajangam K
,
Dimopoulos MA
,
A Stewart K
,
Badros A
,
Papadopoulos KP
et al.
. 2017.
Population Pharmacokinetics and Exposure-Response Relationship of Carfilzomib in Patients With Multiple Myeloma.
.
J Clin Pharmacol. 57(5):663-677.
P
Palumbo A
,
S Rajkumar V
,
San Miguel JF
,
Larocca A
,
Niesvizky R
,
Morgan G
,
Landgren O
,
Hajek R
,
Einsele H
,
Anderson KC
et al.
. 2014.
International Myeloma Working Group consensus statement for the management, treatment, and supportive care of patients with myeloma not eligible for standard autologous stem-cell transplantation.
.
J Clin Oncol. 32(6):587-600.
R
Richardson PG
,
Mark TM
,
Lacy MQ
. 2013.
Pomalidomide: new immunomodulatory agent with potent antiproliferative effects.
.
Crit Rev Oncol Hematol. 88 Suppl 1:S36-44.
Rosenbaum C
,
Jasielec J
,
Laubach J
,
Prada CPaba
,
Richardson P
,
Jakubowiak AJ
. 2013.
Evolving strategies in the initial treatment of multiple myeloma.
.
Semin Oncol. 40(5):592-601.
S
Siegel D
,
Martin T
,
Nooka A
,
R Harvey D
,
Vij R
,
Niesvizky R
,
Badros AZ
,
Jagannath S
,
McCulloch L
,
Rajangam K
et al.
. 2013.
Integrated safety profile of single-agent carfilzomib: experience from 526 patients enrolled in 4 phase II clinical studies.
.
Haematologica. 98(11):1753-61.
A Stewart K
,
Dimopoulos MA
,
Masszi T
,
Spicka I
,
Oriol A
,
Hajek R
,
Rosiñol L
,
Siegel DS
,
Niesvizky R
,
Jakubowiak AJ
et al.
. 2016.
Health-Related Quality-of-Life Results From the Open-Label, Randomized, Phase III ASPIRE Trial Evaluating Carfilzomib, Lenalidomide, and Dexamethasone Versus Lenalidomide and Dexamethasone in Patients With Relapsed Multiple Myeloma.
.
J Clin Oncol. 34(32):3921-3930.
A Stewart K
,
S Rajkumar V
,
Dimopoulos MA
,
Masszi T
,
Spicka I
,
Oriol A
,
Hajek R
,
Rosiñol L
,
Siegel DS
,
Mihaylov GG
et al.
. 2015.
Carfilzomib, lenalidomide, and dexamethasone for relapsed multiple myeloma.
.
N Engl J Med. 372(2):142-52.
V
van Besien K
,
Koshy N
,
Gergis U
,
Mayer S
,
Cushing M
,
Rennert H
,
Reich-Slotky R
,
Mark T
,
Pearse R
,
Rossi A
et al.
. 2017.
Cord blood chimerism and relapse after haplo-cord transplantation.
.
Leuk Lymphoma. 58(2):288-297.
Vij R
,
Wang M
,
Jagannath S
,
Niesvizky R
,
Jakubowiak AJ
,
Kavalerchik E
,
Huang M
,
Siegel DS
. 2015.
Serum free light chain reduction correlates with response and progression-free survival following carfilzomib therapy in relapsed/refractory multiple myeloma.
.
Leuk Lymphoma. 56(10):2959-61.
W
Wang M
,
Martin T
,
Bensinger W
,
Alsina M
,
Siegel DS
,
Kavalerchik E
,
Huang M
,
Orlowski RZ
,
Niesvizky R
. 2013.
Phase 2 dose-expansion study (PX-171-006) of carfilzomib, lenalidomide, and low-dose dexamethasone in relapsed or progressive multiple myeloma.
.
Blood. 122(18):3122-8.
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