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Found 41 results
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]
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2018
Goldschmidt H
,
Moreau P
,
Ludwig H
,
Niesvizky R
,
Chng W-J
,
Joshua D
,
Weisel K
,
Spencer A
,
Orlowski RZ
,
Feng S
et al.
. 2018.
Carfilzomib-dexamethasone versus subcutaneous or intravenous bortezomib in relapsed or refractory multiple myeloma: secondary analysis of the phase 3 ENDEAVOR study.
.
Leuk Lymphoma. 59(6):1364-1374.
Wei X
,
M Calvo-Vidal N
,
Chen S
,
Wu G
,
Revuelta MV
,
Sun J
,
Zhang J
,
Walsh MF
,
Nichols KE
,
Joseph V
et al.
. 2018.
Germline Lysine-Specific Demethylase 1 () Mutations Confer Susceptibility to Multiple Myeloma.
.
Cancer Res. 78(10):2747-2759.
Wei X
,
M Calvo-Vidal N
,
Chen S
,
Wu G
,
Revuelta MV
,
Sun J
,
Zhang J
,
Walsh MF
,
Nichols KE
,
Joseph V
et al.
. 2018.
Germline Lysine-Specific Demethylase 1 () Mutations Confer Susceptibility to Multiple Myeloma.
.
Cancer Res. 78(10):2747-2759.
Wei X
,
M Calvo-Vidal N
,
Chen S
,
Wu G
,
Revuelta MV
,
Sun J
,
Zhang J
,
Walsh MF
,
Nichols KE
,
Joseph V
et al.
. 2018.
Germline Lysine-Specific Demethylase 1 () Mutations Confer Susceptibility to Multiple Myeloma.
.
Cancer Res. 78(10):2747-2759.
2017
Ludwig H
,
Dimopoulos MA
,
Moreau P
,
Chng W-J
,
Goldschmidt H
,
Hajek R
,
Facon T
,
Pour L
,
Niesvizky R
,
Oriol A
et al.
. 2017.
Carfilzomib and dexamethasone vs bortezomib and dexamethasone in patients with relapsed multiple myeloma: results of the phase 3 study ENDEAVOR (NCT01568866) according to age subgroup.
.
Leuk Lymphoma. 58(10):2501-2504.
Dimopoulos MA
,
A Stewart K
,
Masszi T
,
Spicka I
,
Oriol A
,
Hajek R
,
Rosiñol L
,
Siegel D
,
Mihaylov GG
,
Goranova-Marinova V
et al.
. 2017.
Carfilzomib, lenalidomide, and dexamethasone in patients with relapsed multiple myeloma categorised by age: secondary analysis from the phase 3 ASPIRE study.
.
Br J Haematol. 177(3):404-413.
Dimopoulos MA
,
Goldschmidt H
,
Niesvizky R
,
Joshua D
,
Chng W-J
,
Oriol A
,
Orlowski RZ
,
Ludwig H
,
Facon T
,
Hajek R
et al.
. 2017.
Carfilzomib or bortezomib in relapsed or refractory multiple myeloma (ENDEAVOR): an interim overall survival analysis of an open-label, randomised, phase 3 trial.
.
Lancet Oncol. 18(10):1327-1337.
Dimopoulos MA
,
Stewart AK
,
Masszi T
,
Špička I
,
Oriol A
,
Hájek R
,
Rosiñol L
,
Siegel D
,
Mihaylov GG
,
Goranova-Marinova V
et al.
. 2017.
Carfilzomib-lenalidomide-dexamethasone vs lenalidomide-dexamethasone in relapsed multiple myeloma by previous treatment.
.
Blood Cancer J. 7(4):e554.
Nayar U
,
Sadek J
,
Reichel J
,
Hernandez-Hopkins D
,
Akar G
,
Barelli PJ
,
Sahai MA
,
Zhou H
,
Totonchy J
,
Jayabalan D
et al.
. 2017.
Identification of a nucleoside analog active against adenosine kinase-expressing plasma cell malignancies.
.
J Clin Invest. 127(6):2066-2080.
Castillo JJ
,
Jurczyszyn A
,
Brozova L
,
Crusoe E
,
Czepiel J
,
Davila J
,
Dispenzieri A
,
Eveillard M
,
Fiala MA
,
Ghobrial IM
et al.
. 2017.
IgM myeloma: A multicenter retrospective study of 134 patients.
.
Am J Hematol. 92(8):746-751.
Castillo JJ
,
Jurczyszyn A
,
Brozova L
,
Crusoe E
,
Czepiel J
,
Davila J
,
Dispenzieri A
,
Eveillard M
,
Fiala MA
,
Ghobrial IM
et al.
. 2017.
IgM myeloma: A multicenter retrospective study of 134 patients.
.
Am J Hematol. 92(8):746-751.
Moreau P
,
Joshua D
,
Chng W-J
,
Palumbo A
,
Goldschmidt H
,
Hájek R
,
Facon T
,
Ludwig H
,
Pour L
,
Niesvizky R
et al.
. 2017.
Impact of prior treatment on patients with relapsed multiple myeloma treated with carfilzomib and dexamethasone vs bortezomib and dexamethasone in the phase 3 ENDEAVOR study.
.
Leukemia. 31(1):115-122.
2016
A Stewart K
,
Dimopoulos MA
,
Masszi T
,
Spicka I
,
Oriol A
,
Hajek R
,
Rosiñol L
,
Siegel DS
,
Niesvizky R
,
Jakubowiak AJ
et al.
. 2016.
Health-Related Quality-of-Life Results From the Open-Label, Randomized, Phase III ASPIRE Trial Evaluating Carfilzomib, Lenalidomide, and Dexamethasone Versus Lenalidomide and Dexamethasone in Patients With Relapsed Multiple Myeloma.
.
J Clin Oncol. 34(32):3921-3930.
2015
A Stewart K
,
S Rajkumar V
,
Dimopoulos MA
,
Masszi T
,
Spicka I
,
Oriol A
,
Hajek R
,
Rosiñol L
,
Siegel DS
,
Mihaylov GG
et al.
. 2015.
Carfilzomib, lenalidomide, and dexamethasone for relapsed multiple myeloma.
.
N Engl J Med. 372(2):142-52.
Niesvizky R
,
Badros AZ
,
Costa LJ
,
Ely SA
,
Singhal SB
,
Stadtmauer EA
,
Haideri NA
,
Yacoub A
,
Hess G
,
Lentzsch S
et al.
. 2015.
Phase 1/2 study of cyclin-dependent kinase (CDK)4/6 inhibitor palbociclib (PD-0332991) with bortezomib and dexamethasone in relapsed/refractory multiple myeloma.
.
Leuk Lymphoma. 56(12):3320-8.
2014
Palumbo A
,
S Rajkumar V
,
San Miguel JF
,
Larocca A
,
Niesvizky R
,
Morgan G
,
Landgren O
,
Hajek R
,
Einsele H
,
Anderson KC
et al.
. 2014.
International Myeloma Working Group consensus statement for the management, treatment, and supportive care of patients with myeloma not eligible for standard autologous stem-cell transplantation.
.
J Clin Oncol. 32(6):587-600.
Palumbo A
,
S Rajkumar V
,
San Miguel JF
,
Larocca A
,
Niesvizky R
,
Morgan G
,
Landgren O
,
Hajek R
,
Einsele H
,
Anderson KC
et al.
. 2014.
International Myeloma Working Group consensus statement for the management, treatment, and supportive care of patients with myeloma not eligible for standard autologous stem-cell transplantation.
.
J Clin Oncol. 32(6):587-600.
Palumbo A
,
S Rajkumar V
,
San Miguel JF
,
Larocca A
,
Niesvizky R
,
Morgan G
,
Landgren O
,
Hajek R
,
Einsele H
,
Anderson KC
et al.
. 2014.
International Myeloma Working Group consensus statement for the management, treatment, and supportive care of patients with myeloma not eligible for standard autologous stem-cell transplantation.
.
J Clin Oncol. 32(6):587-600.
Kumar SK
,
Berdeja JG
,
Niesvizky R
,
Lonial S
,
Laubach JP
,
Hamadani M
,
A Stewart K
,
Hari P
,
Roy V
,
Vescio R
et al.
. 2014.
Safety and tolerability of ixazomib, an oral proteasome inhibitor, in combination with lenalidomide and dexamethasone in patients with previously untreated multiple myeloma: an open-label phase 1/2 study.
.
Lancet Oncol. 15(13):1503-12.
Kumar SK
,
Berdeja JG
,
Niesvizky R
,
Lonial S
,
Laubach JP
,
Hamadani M
,
A Stewart K
,
Hari P
,
Roy V
,
Vescio R
et al.
. 2014.
Safety and tolerability of ixazomib, an oral proteasome inhibitor, in combination with lenalidomide and dexamethasone in patients with previously untreated multiple myeloma: an open-label phase 1/2 study.
.
Lancet Oncol. 15(13):1503-12.
Kumar SK
,
Berdeja JG
,
Niesvizky R
,
Lonial S
,
Laubach JP
,
Hamadani M
,
A Stewart K
,
Hari P
,
Roy V
,
Vescio R
et al.
. 2014.
Safety and tolerability of ixazomib, an oral proteasome inhibitor, in combination with lenalidomide and dexamethasone in patients with previously untreated multiple myeloma: an open-label phase 1/2 study.
.
Lancet Oncol. 15(13):1503-12.
2013
Badros AZ
,
Vij R
,
Martin T
,
Zonder JA
,
Kunkel L
,
Wang Z
,
Lee S
,
Wong AF
,
Niesvizky R
. 2013.
Carfilzomib in multiple myeloma patients with renal impairment: pharmacokinetics and safety.
.
Leukemia. 27(8):1707-14.
Rosenbaum C
,
Jasielec J
,
Laubach J
,
Prada CPaba
,
Richardson P
,
Jakubowiak AJ
. 2013.
Evolving strategies in the initial treatment of multiple myeloma.
.
Semin Oncol. 40(5):592-601.
Siegel D
,
Martin T
,
Nooka A
,
R Harvey D
,
Vij R
,
Niesvizky R
,
Badros AZ
,
Jagannath S
,
McCulloch L
,
Rajangam K
et al.
. 2013.
Integrated safety profile of single-agent carfilzomib: experience from 526 patients enrolled in 4 phase II clinical studies.
.
Haematologica. 98(11):1753-61.
Richardson PG
,
Mark TM
,
Lacy MQ
. 2013.
Pomalidomide: new immunomodulatory agent with potent antiproliferative effects.
.
Crit Rev Oncol Hematol. 88 Suppl 1:S36-44.
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